src kinase inhibitor 1 ski 1 Search Results


ski 1 inhibitor  (MedChemExpress)
95
MedChemExpress ski 1 inhibitor
Ski 1 Inhibitor, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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src inhibitor 1 ski 1 4 4 phenoxyanilino 6 7 dimethoxyquinazoline  (Selleck Chemicals)
93
Selleck Chemicals src inhibitor 1 ski 1 4 4 phenoxyanilino 6 7 dimethoxyquinazoline
Src Inhibitor 1 Ski 1 4 4 Phenoxyanilino 6 7 Dimethoxyquinazoline, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
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200 µm src inhibitor 1 (ski-1)  (Millipore)
90
Millipore 200 µm src inhibitor 1 (ski-1)
FAK and Src inhibition suppressed angiogenesis in regenerating hearts. (A–C) At 30 dpa, hearts injected for 10 days with PF-573228, a FAK inhibitor (B) (n = 10), or with <t>SKI-1</t> (C) (n = 13), a Src inhibitor, failed to properly regenerate the heart compared with DMSO controls (A) (n = 31). Red arrows delineate scar. (D) Graph showing clot area at 30 dpa after injections of PF-573228 or SKI-1. (E–M) PF-573228 and SKI-1 injections inhibited angiogenesis. (E–G) AFOG staining of hearts at 10 dpa, injected with DMSO (E) (n = 15), PF-573228 (F) (n = 10), or SKI-1 (G) (n = 10). (H–M) Tg(fli1a:EGFP) hearts injected with DMSO (H and K), PF-573228 (I and L), or with SKI-1 (J and M), immunostained for MHC to detect resection plane. White arrows indicate new vessels formed inside the clot. (N) Quantification fli1a+:EGFP area in the clot at 10 dpa. FAK and Src inhibition significantly reduced new vessel formation. Black boxes delimitate the areas of confocal imaging. Black bars in graphs indicate the mean and error bars the SEM. Scale bars, 100 μm. *P < 0.05; **P < 0.01; ***P < 0.001 one-way ANOVA.
200 µm Src Inhibitor 1 (Ski 1), supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
200 µm src inhibitor 1 (ski-1) - by Bioz Stars, 2026-04
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ski 1 (c src inhibitor 1  (Millipore)
90
Millipore ski 1 (c src inhibitor 1
FAK and Src inhibition suppressed angiogenesis in regenerating hearts. (A–C) At 30 dpa, hearts injected for 10 days with PF-573228, a FAK inhibitor (B) (n = 10), or with <t>SKI-1</t> (C) (n = 13), a Src inhibitor, failed to properly regenerate the heart compared with DMSO controls (A) (n = 31). Red arrows delineate scar. (D) Graph showing clot area at 30 dpa after injections of PF-573228 or SKI-1. (E–M) PF-573228 and SKI-1 injections inhibited angiogenesis. (E–G) AFOG staining of hearts at 10 dpa, injected with DMSO (E) (n = 15), PF-573228 (F) (n = 10), or SKI-1 (G) (n = 10). (H–M) Tg(fli1a:EGFP) hearts injected with DMSO (H and K), PF-573228 (I and L), or with SKI-1 (J and M), immunostained for MHC to detect resection plane. White arrows indicate new vessels formed inside the clot. (N) Quantification fli1a+:EGFP area in the clot at 10 dpa. FAK and Src inhibition significantly reduced new vessel formation. Black boxes delimitate the areas of confocal imaging. Black bars in graphs indicate the mean and error bars the SEM. Scale bars, 100 μm. *P < 0.05; **P < 0.01; ***P < 0.001 one-way ANOVA.
Ski 1 (C Src Inhibitor 1, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ski 1 (c src inhibitor 1 - by Bioz Stars, 2026-04
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src kinase inhibitor 1 ski 1  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology src kinase inhibitor 1 ski 1
FAK and Src inhibition suppressed angiogenesis in regenerating hearts. (A–C) At 30 dpa, hearts injected for 10 days with PF-573228, a FAK inhibitor (B) (n = 10), or with <t>SKI-1</t> (C) (n = 13), a Src inhibitor, failed to properly regenerate the heart compared with DMSO controls (A) (n = 31). Red arrows delineate scar. (D) Graph showing clot area at 30 dpa after injections of PF-573228 or SKI-1. (E–M) PF-573228 and SKI-1 injections inhibited angiogenesis. (E–G) AFOG staining of hearts at 10 dpa, injected with DMSO (E) (n = 15), PF-573228 (F) (n = 10), or SKI-1 (G) (n = 10). (H–M) Tg(fli1a:EGFP) hearts injected with DMSO (H and K), PF-573228 (I and L), or with SKI-1 (J and M), immunostained for MHC to detect resection plane. White arrows indicate new vessels formed inside the clot. (N) Quantification fli1a+:EGFP area in the clot at 10 dpa. FAK and Src inhibition significantly reduced new vessel formation. Black boxes delimitate the areas of confocal imaging. Black bars in graphs indicate the mean and error bars the SEM. Scale bars, 100 μm. *P < 0.05; **P < 0.01; ***P < 0.001 one-way ANOVA.
Src Kinase Inhibitor 1 Ski 1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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src kinase inhibitor 1 ski 1 - by Bioz Stars, 2026-04
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src inhibitor 1 (ski-1  (Millipore)
90
Millipore src inhibitor 1 (ski-1
FAK and Src inhibition suppressed angiogenesis in regenerating hearts. (A–C) At 30 dpa, hearts injected for 10 days with PF-573228, a FAK inhibitor (B) (n = 10), or with <t>SKI-1</t> (C) (n = 13), a Src inhibitor, failed to properly regenerate the heart compared with DMSO controls (A) (n = 31). Red arrows delineate scar. (D) Graph showing clot area at 30 dpa after injections of PF-573228 or SKI-1. (E–M) PF-573228 and SKI-1 injections inhibited angiogenesis. (E–G) AFOG staining of hearts at 10 dpa, injected with DMSO (E) (n = 15), PF-573228 (F) (n = 10), or SKI-1 (G) (n = 10). (H–M) Tg(fli1a:EGFP) hearts injected with DMSO (H and K), PF-573228 (I and L), or with SKI-1 (J and M), immunostained for MHC to detect resection plane. White arrows indicate new vessels formed inside the clot. (N) Quantification fli1a+:EGFP area in the clot at 10 dpa. FAK and Src inhibition significantly reduced new vessel formation. Black boxes delimitate the areas of confocal imaging. Black bars in graphs indicate the mean and error bars the SEM. Scale bars, 100 μm. *P < 0.05; **P < 0.01; ***P < 0.001 one-way ANOVA.
Src Inhibitor 1 (Ski 1, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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src inhibitor 1 (ski-1 - by Bioz Stars, 2026-04
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lfm-a13  (Millipore)
90
Millipore lfm-a13
FAK and Src inhibition suppressed angiogenesis in regenerating hearts. (A–C) At 30 dpa, hearts injected for 10 days with PF-573228, a FAK inhibitor (B) (n = 10), or with <t>SKI-1</t> (C) (n = 13), a Src inhibitor, failed to properly regenerate the heart compared with DMSO controls (A) (n = 31). Red arrows delineate scar. (D) Graph showing clot area at 30 dpa after injections of PF-573228 or SKI-1. (E–M) PF-573228 and SKI-1 injections inhibited angiogenesis. (E–G) AFOG staining of hearts at 10 dpa, injected with DMSO (E) (n = 15), PF-573228 (F) (n = 10), or SKI-1 (G) (n = 10). (H–M) Tg(fli1a:EGFP) hearts injected with DMSO (H and K), PF-573228 (I and L), or with SKI-1 (J and M), immunostained for MHC to detect resection plane. White arrows indicate new vessels formed inside the clot. (N) Quantification fli1a+:EGFP area in the clot at 10 dpa. FAK and Src inhibition significantly reduced new vessel formation. Black boxes delimitate the areas of confocal imaging. Black bars in graphs indicate the mean and error bars the SEM. Scale bars, 100 μm. *P < 0.05; **P < 0.01; ***P < 0.001 one-way ANOVA.
Lfm A13, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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src kinase inhibitor 1 ski1  (Danaher Inc)
86
Danaher Inc src kinase inhibitor 1 ski1
FAK and Src inhibition suppressed angiogenesis in regenerating hearts. (A–C) At 30 dpa, hearts injected for 10 days with PF-573228, a FAK inhibitor (B) (n = 10), or with <t>SKI-1</t> (C) (n = 13), a Src inhibitor, failed to properly regenerate the heart compared with DMSO controls (A) (n = 31). Red arrows delineate scar. (D) Graph showing clot area at 30 dpa after injections of PF-573228 or SKI-1. (E–M) PF-573228 and SKI-1 injections inhibited angiogenesis. (E–G) AFOG staining of hearts at 10 dpa, injected with DMSO (E) (n = 15), PF-573228 (F) (n = 10), or SKI-1 (G) (n = 10). (H–M) Tg(fli1a:EGFP) hearts injected with DMSO (H and K), PF-573228 (I and L), or with SKI-1 (J and M), immunostained for MHC to detect resection plane. White arrows indicate new vessels formed inside the clot. (N) Quantification fli1a+:EGFP area in the clot at 10 dpa. FAK and Src inhibition significantly reduced new vessel formation. Black boxes delimitate the areas of confocal imaging. Black bars in graphs indicate the mean and error bars the SEM. Scale bars, 100 μm. *P < 0.05; **P < 0.01; ***P < 0.001 one-way ANOVA.
Src Kinase Inhibitor 1 Ski1, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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src inhibitor-1  (Aladdin Scientific Corporation)
N/A
Src kinase inhibitor I is a 4-anilinoquinazole competitive inhibitor of Src family tryosine kinases. Src kinase inhibitor I is a dual site inhibitor, described to compete at both the ATP and peptide binding sites of
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Image Search Results


FAK and Src inhibition suppressed angiogenesis in regenerating hearts. (A–C) At 30 dpa, hearts injected for 10 days with PF-573228, a FAK inhibitor (B) (n = 10), or with SKI-1 (C) (n = 13), a Src inhibitor, failed to properly regenerate the heart compared with DMSO controls (A) (n = 31). Red arrows delineate scar. (D) Graph showing clot area at 30 dpa after injections of PF-573228 or SKI-1. (E–M) PF-573228 and SKI-1 injections inhibited angiogenesis. (E–G) AFOG staining of hearts at 10 dpa, injected with DMSO (E) (n = 15), PF-573228 (F) (n = 10), or SKI-1 (G) (n = 10). (H–M) Tg(fli1a:EGFP) hearts injected with DMSO (H and K), PF-573228 (I and L), or with SKI-1 (J and M), immunostained for MHC to detect resection plane. White arrows indicate new vessels formed inside the clot. (N) Quantification fli1a+:EGFP area in the clot at 10 dpa. FAK and Src inhibition significantly reduced new vessel formation. Black boxes delimitate the areas of confocal imaging. Black bars in graphs indicate the mean and error bars the SEM. Scale bars, 100 μm. *P < 0.05; **P < 0.01; ***P < 0.001 one-way ANOVA.

Journal: Cardiovascular Research

Article Title: Extracellular component hyaluronic acid and its receptor Hmmr are required for epicardial EMT during heart regeneration

doi: 10.1093/cvr/cvv190

Figure Lengend Snippet: FAK and Src inhibition suppressed angiogenesis in regenerating hearts. (A–C) At 30 dpa, hearts injected for 10 days with PF-573228, a FAK inhibitor (B) (n = 10), or with SKI-1 (C) (n = 13), a Src inhibitor, failed to properly regenerate the heart compared with DMSO controls (A) (n = 31). Red arrows delineate scar. (D) Graph showing clot area at 30 dpa after injections of PF-573228 or SKI-1. (E–M) PF-573228 and SKI-1 injections inhibited angiogenesis. (E–G) AFOG staining of hearts at 10 dpa, injected with DMSO (E) (n = 15), PF-573228 (F) (n = 10), or SKI-1 (G) (n = 10). (H–M) Tg(fli1a:EGFP) hearts injected with DMSO (H and K), PF-573228 (I and L), or with SKI-1 (J and M), immunostained for MHC to detect resection plane. White arrows indicate new vessels formed inside the clot. (N) Quantification fli1a+:EGFP area in the clot at 10 dpa. FAK and Src inhibition significantly reduced new vessel formation. Black boxes delimitate the areas of confocal imaging. Black bars in graphs indicate the mean and error bars the SEM. Scale bars, 100 μm. *P < 0.05; **P < 0.01; ***P < 0.001 one-way ANOVA.

Article Snippet: To suppress Src Kinase, 3 µL of 200 µM Src Inhibitor 1 (SKI-1) (Sigma) or vehicle DMSO was injected.

Techniques: Inhibition, Injection, Staining, Imaging

HA and its receptor Hmmr are necessary for epicardial cell migration in ex vivo culture. (A–D) Ex vivo epicardial migration assay showing decreased Wt1b:EGFP+ migratory behaviour after hmmrVMO (B) (n = 8) and PF-573228 (D) (n = 7) treatments compared with controls (A) (n = 14) and (C) (n = 7). Images were captured at 3 days post-extraction of the heart. The migration of Wt1b:EGFP+ epicardial cells (red arrows) was measured from Day 1 to Day 3. In control PBS, DMSO, or hmmr-MutMO treatments, epicardial cells migrated on the fibrin-coated plates. In contrast, treatment with hmmrVMO, PF-573228 or SKI-1 significantly suppressed epicardial cell migration. (E–H) Graphs showing migration of Wt1b:EGFP+ cells under various treatments, including suppressing HA production in the hearts with HMC (E) (n = 13), hmmrVMO (F) (n = 8), PF-573228 (G) (n = 7), and with SKI-1, the Src kinase inhibitor (H) (n = 8). Black bars in graphs indicate the mean and error bars the SEM. Scale bars, 250 μm. *P < 0.05; **P < 0.01; ***P < 0.001. Two-way ANOVA.

Journal: Cardiovascular Research

Article Title: Extracellular component hyaluronic acid and its receptor Hmmr are required for epicardial EMT during heart regeneration

doi: 10.1093/cvr/cvv190

Figure Lengend Snippet: HA and its receptor Hmmr are necessary for epicardial cell migration in ex vivo culture. (A–D) Ex vivo epicardial migration assay showing decreased Wt1b:EGFP+ migratory behaviour after hmmrVMO (B) (n = 8) and PF-573228 (D) (n = 7) treatments compared with controls (A) (n = 14) and (C) (n = 7). Images were captured at 3 days post-extraction of the heart. The migration of Wt1b:EGFP+ epicardial cells (red arrows) was measured from Day 1 to Day 3. In control PBS, DMSO, or hmmr-MutMO treatments, epicardial cells migrated on the fibrin-coated plates. In contrast, treatment with hmmrVMO, PF-573228 or SKI-1 significantly suppressed epicardial cell migration. (E–H) Graphs showing migration of Wt1b:EGFP+ cells under various treatments, including suppressing HA production in the hearts with HMC (E) (n = 13), hmmrVMO (F) (n = 8), PF-573228 (G) (n = 7), and with SKI-1, the Src kinase inhibitor (H) (n = 8). Black bars in graphs indicate the mean and error bars the SEM. Scale bars, 250 μm. *P < 0.05; **P < 0.01; ***P < 0.001. Two-way ANOVA.

Article Snippet: To suppress Src Kinase, 3 µL of 200 µM Src Inhibitor 1 (SKI-1) (Sigma) or vehicle DMSO was injected.

Techniques: Migration, Ex Vivo